Consideration Whether Hepatitis B Exists in Children Whose Mothers Suffer from Chronic Hepatitis B and These Mothers in Gestational Age
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Date
2020
Authors
İlknur ESEN YILDIZ
Selma TOSUN
Semra ŞEN
Lütfiye Nilsun ALTUNAL
Kenan UĞURLU
Ayşenur BAHŞİ
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Abstract
Objectives: Perinatal and intrauterine transmission of the hepatitis Bvirus (HBV) represents a major factor, leading to the development ofchronic infection. This study aimed to explore the status of mothersand their children for hepatitis B (HB) infection during pregnancy andchildhood, and whether active and passive immunoprophylaxis wasadministered to infants shortly after birth.Materials and Methods: We performed multicenter, retrospectiveresearch on voluntary hepatitis B surface antigen (HBsAg)-positivemothers admitted to infectious diseases polyclinics was performed.Mothers and their children were queried by a questionnaire abouttheir HB infection status. Data from the electronic data recordingsystem was scanned retrospectively.Results: Three hundred-one mothers and 616 children wereincluded in the study. HBsAg was examined in 354 (57.4%) ofpregnancies. Of 91 children with HBsAg positivity, 83 were notapplied active and passive immunoprophylaxis after birth. Eight 276babies received both immune prophylaxes after birth were thendetected as HBsAg positive. On HBV examination, 148 childrenwere found to encounter the HBV. HBsAg positivity rate wassignificantly higher in children born before 1997.Conclusion: The remarkable decrease in HBsAg positivity ofchildren reveals the efficacy of national vaccination. By informingboth healthcare workers and society, awareness about examiningpregnants for HBsAg during pregnancy should be increased.