A comparative study of azithromycin, cephalexin and penicillin V for the treatment of streptococcal pharyngitis and tonsillitis in children; [COCUKLARDA STREPTOKOKSIK FARENJIT VE TONSILLIT TEDAVISINDE AZITROMISIN, SEFALEKSIN VE ORAL PENISILIN VNIN ETKINLIGININ KARSILASTIRILMASI]

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dc.contributor.authorEce A.
dc.contributor.authorIscan A.
dc.contributor.authorSengil A.Z.
dc.contributor.authorBalkan C.
dc.contributor.authorCetinkaya Z.
dc.date.accessioned2024-07-22T08:26:00Z
dc.date.available2024-07-22T08:26:00Z
dc.date.issued1996
dc.description.abstractIn this study, clinical and bacteriological efficacies of penicillin V were compared with those of azithromycin and cephalexin. Of 94 children who had group A beta hemolytic streptococcal (GABHS) pharyngitis/tonsillitis, 31 received a single daily. dose of azithromycin (10 mg/kg) for three days, 33 received cephalexin 40 mg/kg/day in three doses for 10 days, 30 received oral penicillin V 50.000 IU/kg for 10 days. At the end of the treatment, bacterial eradication was achieved in 91% of azithromycin-treated patients, 88% of cephalexin-treated patients and 83% of penicillin treated-patients (p > 0.05). Clinical cure rates were 94% in azithromycin group, 91% in cephalexin group and 90% in penicillin group (p > 0.05). At follow-up evaluation (day 30 ± 5) bacteriologic recurrence was observed in 4 patients of azithromycin-treated group (13%), in 6 of cephalexin treated group (18%) and in 6 of penicillin-treated group (20%). The results of this study indicate that oral penicillin V is clinically as effective as azithromycin and cephalexin in the treatment of GABHS pharyngotonsillitis.
dc.identifier.issn03749096
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20697
dc.language.isoTurkish
dc.subjectazithromycin
dc.subjectcefalexin
dc.subjectpenicillin v
dc.subjectadolescent
dc.subjectarticle
dc.subjectchild
dc.subjectdrug efficacy
dc.subjectfemale
dc.subjecthemolytic streptococcus
dc.subjecthuman
dc.subjectinfant
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectoral drug administration
dc.subjectpharyngitis
dc.subjecttonsillitis
dc.titleA comparative study of azithromycin, cephalexin and penicillin V for the treatment of streptococcal pharyngitis and tonsillitis in children; [COCUKLARDA STREPTOKOKSIK FARENJIT VE TONSILLIT TEDAVISINDE AZITROMISIN, SEFALEKSIN VE ORAL PENISILIN VNIN ETKINLIGININ KARSILASTIRILMASI]
dc.typeArticle

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