Radiotherapy and Immmun Responce is the Radiotherapy Vaccine? Good News?
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Date
2019
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Abstract
Radiotherapy (RT) activates immun responce. Because of this we must discuss the question of “is the radiotherapy vaccine”. If RT increases the immun response we must learn some more about the RT effects on the cells, cell surface antigene, immun checkpoints and their inhibition (ICI; CTLA4, PD1, PDL1 inhibition). In this review it will be discussed the role of the radiotherapy and biologic effects of the radiotherapy to activate the immun responce, radiotherapy dose, radiotherapy timing and the side effects of immun checkpoints inhibitors.