Maternal serum perlecan levels in women with preeclampsia

dc.contributor.authorAkbas M.
dc.contributor.authorKoyuncu F.M.
dc.contributor.authorArtunc-Ulkumen B.
dc.contributor.authorTaneli F.
dc.contributor.authorOzdemir H.
dc.date.accessioned2025-04-10T11:06:40Z
dc.date.available2025-04-10T11:06:40Z
dc.date.issued2020
dc.description.abstractObjective: Perlecan is an extracellular matrix proteoglycan suggested to maintain endothelial functions. We aimed to measure maternal serum perlecan levels in different preeclampsia phenotypes. Methods: This study included 50 women with preeclampsia and 30 healthy pregnant women. Results: Serum perlecan levels were significantly higher (p = 0.016) in preeclamptic women with severe features(n = 23) than preeclampsia patients(n = 27). There were no statistically significant differences in serum perlecan levels between the early-onset preeclampsia(n = 25), late-onset preeclampsia(n = 25), and healthy pregnancies. Conclusion: Our findings suggest that preeclamptic women with severe features have higher serum perlecan levels than women with preeclampsia. © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group.
dc.identifier.DOI-ID10.1080/10641955.2019.1711390
dc.identifier.urihttp://hdl.handle.net/20.500.14701/46849
dc.publisherTaylor and Francis Ltd
dc.titleMaternal serum perlecan levels in women with preeclampsia
dc.typeArticle

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