Predictive Value of Mean Platelet Volume and Platelet Levels for Preeclampsia
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Date
2022
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Abstract
Objective: Preeclampsia is a pregnancy-specific disease with hypertension, proteinuria, and/or organ damage. This study aimed to investigate whether preeclampsia is predictable or not based on some hematological parameters at primary care units step where routine follow-ups are made during the pregnancy.
Materials and methods: In this retrospective study, 58 pregnant women with preeclampsia and 116 healthy pregnant women were included. Two different hemogram results belonging to the time of diagnosis and 2-6 weeks before diagnosis in the preeclampsia group; and two different hemogram results belonging to the time of delivery and 2-6 weeks before delivery for the control group were included in the study.
Results: It was determined that MPV levels were higher; platelet count, NLR, and PLR levels were lower in the second hemogram results compared with the first hemogram results of the preeclampsia group. The ROC analysis result, it was revealed that the sensitivity and specificity of MPV for predicting preeclampsia were 75,9% and 33,3%, respectively, when the cut-off value of MPV was accepted as 8,95 (fL).
Conclusion: When we compared the results of our study with the literature, it was evaluated that MPV, NLR, and PLR data could be used for the prediction of preeclampsia patients. It has been required for a long duration of studies
that need a large number of patients to use the tendency in an increase of MPV and the decrease of NLR and PLR for prediction of preeclampsia.