Postoperative analgesic effects of intraarticular morphine and neostigmine after arthroscopy
| dc.contributor.author | Tekin I. | |
| dc.contributor.author | Ongun B. | |
| dc.contributor.author | Kafesçiler K. | |
| dc.date.accessioned | 2025-04-10T11:18:13Z | |
| dc.date.available | 2025-04-10T11:18:13Z | |
| dc.date.issued | 2002 | |
| dc.description.abstract | Postoperative analgesic effect of intraarticular morphine and neostigmine after arthroscopy were compared. We studied 60 patients, undergoing elective knee arthroscopy. A standardized general anesthetic was administered. Patients were allocated to 3 groups at the end of the surgery. Group K (control, n=20) recieved 20 mL 0.9% saline, group M (morphine, n=20) recieved 1 mg morphine in 20 mL 0.9% saline and Group N (neostigmine. n=20) recieved 0.5 mg neostigmine in 20 mL 0.9% saline intraarticularly, 10 minutes before the limb tourniquet was deflated. Postoperative pain scores were recorded at the end of the surgery, at 30. min, 1., 2., 4., 6. and 12. hours postoperatively by VAS. Heart rate, mean arterial pressure, breathing rate and adverse effects were also recorded at the same times. Additional analgesic requirements, total analgesic consumption and first analgesic administration time were settled. There were no significant differences in hemodynamic parameters and additional analgesic requirements between the Group M and Group N. VAS scores on flexion and extention were significantly lower in group M and N compared with group K at postop 30. min. At subsequent measurements, VAS scores on extention were lower in group M and N according to group K. Additional analgesic administration was very high in group K, compared with the othe groups. First analgesic administration time was not different between Group M and N. Patients didn't complain from any adverse effects. Finally, we conclude that İntraarticular low-dose (1 mg) morphine and 0.5 mg neostigmine produce significant analgesic effect compared with placebo but they are not superior each other. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/53294 | |
| dc.title | Postoperative analgesic effects of intraarticular morphine and neostigmine after arthroscopy | |
| dc.type | Article |