Comparison of high-sensitivity C-reactive protein and fetuin-A levels before and after treatment for subjects with subclinical hyperthyroidism
| dc.contributor.author | Bilgir O. | |
| dc.contributor.author | Bilgir F. | |
| dc.contributor.author | Topcuoglu T. | |
| dc.contributor.author | Calan M. | |
| dc.contributor.author | Calan O. | |
| dc.date.accessioned | 2025-04-10T11:13:18Z | |
| dc.date.available | 2025-04-10T11:13:18Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | This study was designed to show the effect of propylthiouracil treatment on sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels on subjects with subclinical hyperthyroidism. After checking sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels of 35 patients with subclinical hyperthyroidism, each was given 50 mg tablets of propylthiouracil three times daily. After 3 months, sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels were then compared to the levels before treatment. Although high-sensitivity C-reactive protein and sCD40L levels were normal in the subclinical hyperthyroidism patients compared to the healthy controls, fetuin-A levels were statistically significantly higher (*p = 0.022). After treatment, fetuin-A levels of subclinical hyperthyroidism patients decreased statistically significantly compared to the levels before treatment (**p = 0.026). sCD40L and high-sensitivity C-reactive protein levels did not have a statistically significant difference compared to the control group and post-propylthiouracil treatment. In subclinical hyperthyroidism patients, high fetuin-A levels before propylthiouracil treatment and decreases in these levels after treatment in cases with subclinical hyperthyroidism indicated the possibility of preventing long-term cardiac complications with propylthiouracil treatment. © 2013 Springer Science+Business Media New York. | |
| dc.identifier.DOI-ID | 10.1007/s12020-013-9993-z | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/49838 | |
| dc.publisher | Humana Press Inc. | |
| dc.title | Comparison of high-sensitivity C-reactive protein and fetuin-A levels before and after treatment for subjects with subclinical hyperthyroidism | |
| dc.type | Article |