A Retrospective Analysis of 83 Patients with Testicular Mass Who Underwent Testis-Sparing Surgery: The Eurasian Uro-oncology Association Multicenter Study
dc.contributor.author | Keske, M | |
dc.contributor.author | Canda, AE | |
dc.contributor.author | Karadag, MA | |
dc.contributor.author | Çiftçi, H | |
dc.contributor.author | Erturhan, S | |
dc.contributor.author | Kactan, C | |
dc.contributor.author | Soytas, M | |
dc.contributor.author | Özkaya, F | |
dc.contributor.author | Ozbey, I | |
dc.contributor.author | Ordek, E | |
dc.contributor.author | Atmaca, AF | |
dc.contributor.author | Yildirim, A | |
dc.contributor.author | Sahin, S | |
dc.contributor.author | Colakoglu, Y | |
dc.contributor.author | Boylu, U | |
dc.contributor.author | Erol, B | |
dc.contributor.author | Caskurlu, T | |
dc.contributor.author | Kiremit, MC | |
dc.contributor.author | Cakici, OU | |
dc.contributor.author | Sonmez, G | |
dc.contributor.author | Kiliçarslan, H | |
dc.contributor.author | Akbulut, Z | |
dc.contributor.author | Kaygisiz, O | |
dc.contributor.author | Bedir, S | |
dc.contributor.author | Vuruskan, H | |
dc.contributor.author | Bozkurt, YE | |
dc.contributor.author | Aydin, HR | |
dc.contributor.author | Oguz, U | |
dc.contributor.author | Basok, EK | |
dc.contributor.author | Gumus, BH | |
dc.contributor.author | Tuncel, A | |
dc.contributor.author | Aslan, Y | |
dc.contributor.author | Hamidi, N | |
dc.contributor.author | Müslümanoglu, AY | |
dc.contributor.author | Dinçer, M | |
dc.contributor.author | Balbay, D | |
dc.contributor.author | Albayrak, S | |
dc.contributor.author | Laguna, MP | |
dc.date.accessioned | 2024-07-18T12:08:12Z | |
dc.date.available | 2024-07-18T12:08:12Z | |
dc.description.abstract | Introduction: Herein, we analyzed the histopathological, oncological and functional outcomes of testis-sparing surgery (TSS) in patients with distinct risk for testicular cancer. Methods: This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk testicular germ cell tumor (TGCT) according to the presence/absence of features compatible with testicular dysgenesis syndrome. Histology was categorized per size and risk groups. Results: TSS was performed in 83 patients (86 tumors) of them, 27 in the high-risk group. Fifty-nine patients had a non-tumoral contralateral testis present. Sixty masses and 26 masses were benign and TGCTs, respectively. No statistical differences were observed in mean age (30.9 +/- 10.32 years), pathological tumor size (14.67 +/- 6.7 mm) between risk groups or between benign and malignant tumors (p = 0.608). When categorized per risk groups, 22 (73.3%) and 4 (7.1%) of the TSS specimens were malignant in the high- and low-risk patient groups, respectively. Univariate analysis showed that the only independent variable significantly related to malignant outcome was previous history of TGCT. During a mean follow-up of 25.5 +/- 22.7 months, no patient developed systemic disease. Local recurrence was detected in 5 patients and received radical orchiectomy. Postoperative testosterone levels remained normal in 88% of those patients with normal preoperative level. No erectile dysfunction was reported in patients with benign lesions. Conclusion: TSS is a safe and feasible approach with adequate cancer control, and preservation of sexual function is possible in 2/3 of patients harboring malignancy. Incidence of TGCT varies extremely between patients at high and low risk for TGCT requiring a careful consideration and counseling. | |
dc.identifier.issn | 0042-1138 | |
dc.identifier.other | 1423-0399 | |
dc.identifier.uri | http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/10850 | |
dc.language.iso | English | |
dc.publisher | KARGER | |
dc.subject | TUMORS | |
dc.subject | PREVALENCE | |
dc.subject | NEOPLASIA | |
dc.subject | CANCER | |
dc.title | A Retrospective Analysis of 83 Patients with Testicular Mass Who Underwent Testis-Sparing Surgery: The Eurasian Uro-oncology Association Multicenter Study | |
dc.type | Article |