A Retrospective Analysis of 83 Patients with Testicular Mass Who Underwent Testis-Sparing Surgery: The Eurasian Uro-oncology Association Multicenter Study

dc.contributor.authorKeske, M
dc.contributor.authorCanda, AE
dc.contributor.authorKaradag, MA
dc.contributor.authorÇiftçi, H
dc.contributor.authorErturhan, S
dc.contributor.authorKactan, C
dc.contributor.authorSoytas, M
dc.contributor.authorÖzkaya, F
dc.contributor.authorOzbey, I
dc.contributor.authorOrdek, E
dc.contributor.authorAtmaca, AF
dc.contributor.authorYildirim, A
dc.contributor.authorSahin, S
dc.contributor.authorColakoglu, Y
dc.contributor.authorBoylu, U
dc.contributor.authorErol, B
dc.contributor.authorCaskurlu, T
dc.contributor.authorKiremit, MC
dc.contributor.authorCakici, OU
dc.contributor.authorSonmez, G
dc.contributor.authorKiliçarslan, H
dc.contributor.authorAkbulut, Z
dc.contributor.authorKaygisiz, O
dc.contributor.authorBedir, S
dc.contributor.authorVuruskan, H
dc.contributor.authorBozkurt, YE
dc.contributor.authorAydin, HR
dc.contributor.authorOguz, U
dc.contributor.authorBasok, EK
dc.contributor.authorGumus, BH
dc.contributor.authorTuncel, A
dc.contributor.authorAslan, Y
dc.contributor.authorHamidi, N
dc.contributor.authorMüslümanoglu, AY
dc.contributor.authorDinçer, M
dc.contributor.authorBalbay, D
dc.contributor.authorAlbayrak, S
dc.contributor.authorLaguna, MP
dc.date.accessioned2024-07-18T12:08:12Z
dc.date.available2024-07-18T12:08:12Z
dc.description.abstractIntroduction: Herein, we analyzed the histopathological, oncological and functional outcomes of testis-sparing surgery (TSS) in patients with distinct risk for testicular cancer. Methods: This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk testicular germ cell tumor (TGCT) according to the presence/absence of features compatible with testicular dysgenesis syndrome. Histology was categorized per size and risk groups. Results: TSS was performed in 83 patients (86 tumors) of them, 27 in the high-risk group. Fifty-nine patients had a non-tumoral contralateral testis present. Sixty masses and 26 masses were benign and TGCTs, respectively. No statistical differences were observed in mean age (30.9 +/- 10.32 years), pathological tumor size (14.67 +/- 6.7 mm) between risk groups or between benign and malignant tumors (p = 0.608). When categorized per risk groups, 22 (73.3%) and 4 (7.1%) of the TSS specimens were malignant in the high- and low-risk patient groups, respectively. Univariate analysis showed that the only independent variable significantly related to malignant outcome was previous history of TGCT. During a mean follow-up of 25.5 +/- 22.7 months, no patient developed systemic disease. Local recurrence was detected in 5 patients and received radical orchiectomy. Postoperative testosterone levels remained normal in 88% of those patients with normal preoperative level. No erectile dysfunction was reported in patients with benign lesions. Conclusion: TSS is a safe and feasible approach with adequate cancer control, and preservation of sexual function is possible in 2/3 of patients harboring malignancy. Incidence of TGCT varies extremely between patients at high and low risk for TGCT requiring a careful consideration and counseling.
dc.identifier.issn0042-1138
dc.identifier.other1423-0399
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/10850
dc.language.isoEnglish
dc.publisherKARGER
dc.subjectTUMORS
dc.subjectPREVALENCE
dc.subjectNEOPLASIA
dc.subjectCANCER
dc.titleA Retrospective Analysis of 83 Patients with Testicular Mass Who Underwent Testis-Sparing Surgery: The Eurasian Uro-oncology Association Multicenter Study
dc.typeArticle

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