Browsing by Subject "International Index of Erectile Function"
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Item Does late-onset hypogonadism occur by aging? The evaluation of IIEF, Ams-Q and biochemical parameters; [Yaşlanmayla geç başlayan hipogonadizm oluşuyor mu? IIEF, Ams-Q ve biyokimyasal deǧerlendirilmesi](Turkiye Klinikleri, 2010) Üçer O.; Gümüş B.; Okur M.; Karataş T.C.; Büyüksu C.Objective: The aim of this study is to investigate whether biochemical (hormonal) hypogonadism occurs by aging and whether AMS-Q (Aging Male Symptoms-Questionnaire) and IIEF (International Index of Erectile Function) forms are adequate in order to evaluate its presence in case it occurs. Material and Methods: A total of 182 males who applied to the outpatient clinics of Urology Department and whose ages were between 45-90 years were included in the study. Those who had diabetes mellitus, hypertension, coronary artery disease, dyslipidemia, any psychiatric disorder and any malignancy were excluded. The patients were classified into three groups (Group 1; 45-54, Group 2; 55-64 and Group 3; over 65 years). All participants were asked to complete IIEF and AMS-Q forms and serum levels of total testosterone, free testosterone, LH, DHEA-S, SHBG and prolactin were measured. Results: Total testosterone and prolactin levels did not change with aging. Although free testosterone, bio-available testosterone and DHEA-S levels decreased with age, it was detected that LH and SHBG levels were increased. While IIEF scores decreased with age, however AMS-Q scores did not change. When subgroups of AMS-Q were taken into consideration, sexual scores increased, and a decrease in somatic and psychological scores was detected. There was a strong relationship between IIEF-EF (erectile function) and AMS-Sexual forms. Conclusion: All of the data indicate that secondary hypogonadism occurs by aging and consequent symptoms (especially sexual ones) can be evaluated with IIEF and AMS-Sexual forms. © 2010 by Türkiye Klinikleri.Item Association of angiotensin-converting enzyme I/D and eNOS G894T gene polymorphisms with erectile dysfunction; [Converting enzim I/D ve eNOS G894T gen polimorfızmlerinin erektil disfonksiyon ile ilişkisi](Turkiye Klinikleri, 2011) Çam F.S.; Gümüş B.H.; Var A.; Berdeli A.Objective: Recent studies suggest that angiotensin II and nitric oxide (NO) may modulate penile smooth muscle tone and contractility. Because genotypes of the angiotensin converting enzyme (ACE) and endothelial nitric oxide synthase (eNOS) polymorphisms have been associated with disorders in the vascular system, in this study, we investigated an association between the ACE I/D and eNOS G894T gene polymorphisms and erectile dysfunction (ED). Material and Methods: A total of 44 patients and 45 control subjects were included in the study. Diagnosis of erectile dysfunction (< 26) was provided by International Index of Erectile Function (IIEF). The ACE I/D ve eNOS G894T gene polymorphisms were genotyped using PCR and RFLP. Results: No significant case-control difference was observed for the ACE I/D and eNOS G894T gene polymorphisms either by genotype or allele frequencies [(ACE I/D-X2= 0.930 p= 0.628) and eNOS 894 G/T-X2= 2.114 p = 0.348)]. In addition, there was no significant difference between ACE I/D (X2= 3.174 p= 0.787) and eNOS G894T (X2= 4.320 p= 0.633) and IIEF scores among the patient group. Conclusion: In this study, no association was found between ACE I/D and eNOS G894T gene polymorphisms and erectile dysfunction in the Turkish population studied. © 2011 by Türkiye Klinikleri.Item Erectile function and late-onset hypogonadism symptoms related to lower urinary tract symptom severity in elderly men(2013) Bozkurt O.; Bolat D.; Demir O.; Ucer O.; Şahin A.; Ozcift B.; Pektaş A.; Turan T.; Gümüş B.H.; Can E.; Bolukbasi A.; Erol H.; Esen A.The aim of this study was to evaluate the relationship between lower urinary tract symptoms (LUTSs), erectile dysfunction (ED) and symptomatic late-onset hypogonadism (SLOH) in ageing men in the Aegean region of Turkey. Five hundred consecutive patients >40 years old who had been in a steady sexual relationship for the past 6 months and were admitted to one of six urology clinics were included in the study. Serum prostate-specific antigen and testosterone levels and urinary flow rates were measured. All patients filled out the International Prostate Symptom Score and Quality of Life (IPSS-QoL), International Index of Erectile Function (IIEF) and Aging Males' Symptoms (AMS) scale forms. Of the patients, 23.9% had mild LUTSs, 53.3% had moderate LUTSs and 22.8% had severe LUTSs. The total testosterone level did not differ between groups. Additionally, 69.6% had ED. The presence of impotence increased with increasing LUTS severity. Symptomatic late-onset hypogonadism (AMS >27) was observed in 71.2% of the patients. The prevalence of severe hypogonadism symptoms increased with the IPSS scores. A correlation analysis revealed that all three questionnaire scores were significantly correlated. In conclusion, LUTS severity is an age-independent risk factor for ED and SLOH. LUTS severity and SLOH symptoms appear to have a strong link that requires etiological and biological clarification in future studies. © 2013 AJA, SIMM & SJTU. All rights reserved.Item Sexual function and hormone profile in young adult men with idiopathic gynecomastia: Comparison with healthy controls(IOS Press, 2016) Sir E.; Üçer O.; Aksoy A.; Güngör M.; Ceylan Y.Objectives: To compare sexual function and hormone profile in male patients with gynecomastia with matched controls. MATERIALS-METHODS: Forty-seven male subjects with gynecomastia and thirty healthy controls were enrolled in this study. Serum free T3, free T4, TSH, FSH, prolactin, estradiol, total testosterone, free testosterone, DHEA-SO4, LH and total PSA were measured in the patients and controls. Sexual function of the patients and controls were evaluated using International Index of Erectile Function (IIEF). The hormone values and IIEF scores of the patients were statistically compared with the controls'. RESULTS: The mean of age, body mass index, right and left testicular volume in the patient and control group were similar. The mean FSH and free T3 values of the patients were significantly lower than the controls (p = 0:007 and p = 0:03, respectively). The mean of the other hormone values in the both groups were found to be statistically similar (p > 0:05). The mean ±SD of total IIEF scores in the patient and control group were 60:14 ± 8:78 and 65:24 ± 5:52, respectively (p = 0:007). Although the mean IIEF-erectile function, orgasmic function and intercourse satisfaction scores in the patient group were significantly lower than the control group (p < 0:001, p = 0:004 and p = 0:001, respectively), the mean IIEF-desire score of the patients was significantly higher than the controls (p = 0:002). CONCLUSION: We found that the hormone profiles (except FSH and free T3) of the patients with gynecomastia were similar with the controls. However, gynecomastia adversely affected male sexual function. © 2016-IOS Press and the authors. All rights reserved.Item The Effect of Hyperbaric Oxygen Therapy on Erectile Functions: A Prospective Clinical Study(S. Karger AG, 2018) Sahin M.O.; Sen V.; Eser E.; Koc E.; Gumus U.; Karakuzu C.; Ucer O.Introduction: We aimed to evaluate the effects of hyperbaric oxygen therapy (HBOT) on erectile function in patients who had no cavernosal or urethral injury by using International Index of Erectile Function (IIEF) questionnaire. Materials and Methods: The male patients who were treated by HBOT for several diseases between July 2017 and September 2017 were examined. All patients filled the IIEF questionnaire form before the first day and after the last day of HBOT and a questionnaire including demographic characteristics and medical history. The effects of demographic characteristics and risk factors on erectile function were evaluated, and the IIEF domain scores of patients in first day and last day of HBOT were compared. Results: Totally, 50 patients were included in the study between July 2017 and September 2017 and the mean age was 59.38 ± 13.77. The mean post-HBOT IIEF-EF score of patients was significantly higher than the mean pre-HBOT IIEF-EF score of patients (15.74 ± 10.52 vs. 19.50 ± 10.91; p < 0.001). The mean post-HBOT IIEF scores of other domains including intercourse satisfaction, orgasmic function, sexual desire, and overall satisfaction were also significantly higher than pre-HBOT scores. Conclusions: HBOT may be a good alternative treatment or adjunctive treatment for erectile dysfunction. © 2018 2018 S. Karger AG, Basel.Item Comparison of pain, quality of life, lower urinary tract symptoms and sexual function between flexible and rigid cystoscopy in follow-up male patients with non muscle invasive bladder cancer: A randomized controlled cross section single blind study(John Wiley and Sons Inc, 2021) Ucer O.; Temeltas G.; Gumus B.; Muezzinoglu T.Objectives: To compare pain, quality of life (QoL), sexual function and lower urinary tract symptoms (LUTS) between rigid (RC) and flexible cystoscopy (FC). Methods: Forty-one patients who were planned control cystoscopies were enrolled the study. At the first cystoscopy, 20 patients (Group 1) and other 21 patients (Group 2) were performed by flexible (15.5 Fr) and rigid cystoscope (15.5 Fr), respectively. At the second cystoscopies, the patients in group 1 and group 2 were performed by rigid and flexible cystosacope, respectively. In all the patients, pain was measured with visual pain scale (VPS) shortly after cystoscopy. Also, SF, QoL and LUTS were assessed by IIEF, SF-36 and MLUTS forms, respectively. Results: While 22 of the patients preferred FC, the other 19 preferred RC (P > 0.05). There were no statistical differences between VPS, IIEF, SF-36 and MLUTS scores of the two groups. In multivariate analysis regarding the quality of life, although sexual function, pain and cystoscopy type did not affect QoL, voiding symptoms affected independently QoL. After both cystoscopy type, IIEF, SF-36 and MLUTS scores did not change statistically. Conclusion: The results showed that the effects on pain, sexual function, QoL and LUTS of RC and FC were similar. In general, cystoscopy did not affect negatively on QoL, sexual function and LUTS of the patients. © 2020 John Wiley & Sons Ltd