COMET, TUNEL, and TEM analysis of an infertile male with short tail sperm

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dc.contributor.authorAYŞEN DURMAZ GÜVEN
dc.contributor.authorSERAP CİLAKER MIÇILI
dc.contributor.authorHAFİZE SEDA VATANSEVER
dc.contributor.authorCumhur GÜNDÜZ
dc.contributor.authorHüsnü Alper BAĞRIYANIK
dc.contributor.authorNurten DİKMEN
dc.contributor.authorEGE NAZAN TAVMERGEN GÖKER
dc.contributor.authorErol TAVMERGEN
dc.date.accessioned2024-07-24T09:09:24Z
dc.date.available2024-07-24T09:09:24Z
dc.date.issued2015
dc.description.abstractMale infertility is correlated with sperm morphology and sperm DNA damage, which are completely different from that of fertile individuals. Anaccurate sperm DNA damage analysis and ultrastructural examination of the ejaculate provide important support in the clinical evaluation. It issupposed that in the near future, the fertilization rate, pregnancy rate, and miscarriages could be predicted using the combination of these typesof tests in assisted reproductive technologies (ARTs). For this purpose, we report a very rare case of an infertile man having short tail sperm. Theinfertile man and his wife underwent in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI). During this process, we examinedthe ultrastructure of the ejaculated sperm with transmission electron microscopy (TEM) and calculated the sperm DNA damage with terminaldeoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and COMET assays. Then, we evaluated the association between sperm DNAdamage and embryo quality.
dc.identifier.issn1309-0399
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/22080
dc.language.isoeng
dc.subject[Fen > Tıp > Kadın Hastalıkları ve Doğum]
dc.titleCOMET, TUNEL, and TEM analysis of an infertile male with short tail sperm
dc.typeOlgu Sunumu

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